Searchable abstracts of presentations at key conferences in endocrinology

ea0073oc5.3 | Oral Communications 5: Thyroid | ECE2021

Derivation of thyroid progenitors from human induced pluripotent stem cells

Posabella Alberto , Undeutsch Hendrik J. , Alber Andrea Brigitta , Hollenberg Anthony N. , Kotton Darrell N.

Despite the availability of synthetic thyroid hormone for therapeutic use, a significant number of patients with hypothyroidism do not feel well on replacement doses of thyroid hormones suggesting that better individualized therapy is needed. For this reason, hypothyroidism resulting from congenital lack of functional thyrocytes, surgical tissue removal, or gland ablation, represents a particularly attractive endocrine disease target that may be conceivably cured by transplant...